Don’t Miss Grey’s Anatomy Season 22 Episode 5: Exact Release Date and Time, Plus Where to Watch
Grey’s Anatomy returns with Season 22 Episode 5, Sometimes I Feel Like a Motherless Child, as Jo takes on a high-stakes case involving a pregnant patient — here’s when it drops and where to watch.
Grey's Anatomy is still going (season 22!), and the next hour lines up more messy cases and messier emotions. Episode 5 is titled "Sometimes I Feel Like a Motherless Child," which tells you the vibe right away.
What to expect in Episode 5
Jo gets the heavy lift this week, juggling a complicated case with a pregnant patient. Over in another wing, Blue and Jules team up on a diabetic case. And Simone walks into a situation that drops an unexpected revelation in her lap. Translation: everyone is busy, and at least one person is going to have their day turned inside out.
When it airs
Thursday, November 6, 2025 on ABC. Here are the U.S. times:
- 10 p.m. ET
- 7 p.m. PT
Where to watch
Live on ABC. If you stream your TV life, Hulu will have it, too. ABC is the broadcast home base; Hulu is the on-demand stop with a pile of shows and originals, including this very long-running drama.
New to Grey's Anatomy?
The show follows the personal and professional chaos of doctors working at Seattle's Grey Sloan Memorial Hospital. Scrubs, scalpel, feelings, repeat.